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Antabuse is widely used for the treatment of alcohol abuse (alcoholism) together with support and counseling. Its active component is disulfiram, it helps people who have been abusing alcohol for long time to overcome this harmful addiction and discontinue its destructive effect on the whole body. It works by blocking certain enzyme involved in the body’s metabolism of alcohol and creating unpleasant adverse reactions that occur when a patient consumes alcohol.

Generic Antabuse 500 mg

Q-ty Price per unit Bonus pills    
90 pills $96.50 $ 1.07 + 8 Bonus pills ADD TO CART
120 pills $111.70 $ 0.93 + 12 Bonus pills / ADD TO CART
270 pills $226.00 $ 0.84 + 20 Bonus pills / ADD TO CART

What is Antabuse?
Antabuse is used as an aid in the management of chronic alcoholism in those patients who want to remain sober so that psychotherapeutic and supportive therapy could be applied to the best advantage. Antabuse is not a cure for alcohol addiction; if it is used alone without proper supportive treatment and motivation, it is unlikely to show any considerable effect for a chronic alcoholic.

How does Antabuse work?
The active component of Antabuse is disulfiram. It works by creating sensitivity to alcohol. When a person drinks alcohol, it is broken down in the body into a chemical substance called acetaldehyde, which is then broken down further in order to be removed from the body. Disulfiram inhibits the enzyme that breaks down acetaldehyde and thus leads to an increased level of this substance in the body. That causes unpleasant physical reactions that should stop a person from further drinking. Such reactions vary from person to person, so the whole range of disulfiram-alcohol reactions should be explained by a doctor.

How should Antabuse be taken?
The therapy with the use of Antabuse usually starts in a specialized clinic or a hospital. A patient should undergo detoxification before starting the treatment. The initial dose and dosage regimen should be decided by a doctor.

What side effects can Antabuse provoke?
The side effects of Antabuse include:

  • headaches;
  • fatigue and feeling sleepy;
  • garlic or metallic taste in the mouth;
  • allergic reactions like itching;
  • decreased libido;
  • feeling sick;
  • mood changes;
  • weakness, tingling or loss of sensation in feet and hands;
  • upset stomach, etc.
Adverse reactions of Antabuse are usually minor; however, patients should be monitored for hepatotoxicity because in rare cases it can cause damage to the liver resulting in hepatitis or liver failure.

What are the contraindications to taking Antabuse?
Being a good aid in the fight against alcohol addiction, Antabuse is not good for everyone. The preparation should not be taken by people who have:
  • allergy to disulfiram;
  • cardiovascular problems including hypertension, heart failure, history of heart attack or stroke;
  • severe personality or psychiatric disorder, risk of suicide;
  • epilepsy;
  • recently received alcohol-containing medications, paraldehyde, metronidazole;
Antabuse is also contraindicated in pregnant and breastfeeding females. Extreme caution should be taken if a patient has diabetes or a history of liver or kidney disease.